592 Fingernail photo-onycholysis resulting from aminolevulinic acid-photodynamic therapy with blue light for treatment of actinic keratoses on face
نویسندگان
چکیده
منابع مشابه
Aminolevulinic acid (Levulan) in photodynamic therapy of actinic keratoses.
The role of photodynamic therapy (PDT) in the treatment of in situ neoplasias and tumors of the skin is steadily increasing. Its principles of photodynamic action include an intratumoral enriched photosensitizer and light activation. Aminolevulinic acid (ALA) has demonstrated highest efficacy in topical PDT, and has become the most clinically useful. For actinic (solar) keratoses, topical ALA-P...
متن کاملRandomized Vehicle-Controlled Study of Short Drug Incubation Aminolevulinic Acid Photodynamic Therapy for Actinic Keratoses of the Face or Scalp
BACKGROUND Aminolevulinic acid photodynamic therapy (ALA-PDT) can be effective and well tolerated when applied over a broad area and for short drug incubation times. OBJECTIVE To evaluate the effect of short-incubation time and application method on the safety and efficacy of ALA-PDT versus vehicle (VEH-PDT) in the treatment of actinic keratoses (AKs) of the face or scalp. METHODS Aminolevu...
متن کاملLaser-mediated photodynamic therapy of actinic keratoses.
OBJECTIVE To assess the safety and efficacy of the long-pulsed pulsed dye laser (LP PDL) (595 nm) with photodynamic therapy (PDT) for treatment of actinic keratoses (AKs). DESIGN Prospective, controlled study with 10-day and 2-, 4-,6-, and 8-month follow-ups. SETTING Clinical research center. PATIENTS Volunteer sample of 41 patients (age range, 35-91 years; skin types I-III) with AKs. INT...
متن کاملPhotodynamic therapy with delta-aminolevulinic acid and light-emitting diodes in actinic keratosis.
BACKGROUND Photodynamic therapy is a form of treatment in which a photosensitizing substance is applied to tissue and activated by a light source at a specific wavelength, thus selectively destroying cells. New light sources are being evaluated for use in the treatment of actinic keratoses. OBJECTIVES To evaluate the efficacy of photodynamic therapy with delta-aminolevulinic acid using a ligh...
متن کاملPhotodynamic therapy with aminolevulinic acid topical solution and visible blue light in the treatment of multiple actinic keratoses of the face and scalp: investigator-blinded, phase 3, multicenter trials.
OBJECTIVE To determine the safety and efficacy of photodynamic therapy (PDT) using 20% wt/vol aminolevulinic acid hydrochloride (hereinafter "ALA") and visible blue light for the treatment of multiple actinic keratoses of the face and scalp. DESIGN Randomized, placebo-controlled, uneven parallel-group study. INTERVENTIONS Patients (N = 243) were randomized to receive vehicle or ALA followed...
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ژورنال
عنوان ژورنال: Journal of Investigative Dermatology
سال: 2016
ISSN: 0022-202X
DOI: 10.1016/j.jid.2016.02.631